A Case of Thymoma with Immunodeficiency (Good's Syndrome) with Disseminated Tuberculosis.
10.3904/kjm.2013.85.3.329
- Author:
Hyeon JUNG
1
;
Kyung Mok SOHN
;
Yeon Sook KIM
;
Chang Hun SONG
;
Eun Hee SOHN
Author Information
1. Division of Infectious Diseases, Chungnam National University Hospital, Daejon, Korea. medone@cnuh.co.kr
- Publication Type:Case Report
- Keywords:
Immunologic deficiency syndromes;
Thymoma;
Tuberculosis;
Opportunistic infections
- MeSH:
Agammaglobulinemia;
Aged;
B-Lymphocytes;
Female;
Humans;
Immunoglobulins;
Immunologic Deficiency Syndromes;
Opportunistic Infections;
T-Lymphocytes;
Thymectomy;
Thymoma;
Tuberculosis
- From:Korean Journal of Medicine
2013;85(3):329-333
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Good's syndrome is the rare association of immunodeficiency with thymoma, characterized by hypogammaglobulinemia, depleted B-cells, diminished T-cells and inversion of the CD4/CD8 ratio. Thymectomy does not usually improve hypogammaglobulinemia; thus, the patient remains prone to infections. Infections affect primarily the sinopulmonary and gastrointestinal system. Here we present a case of a 71-year-old woman with common manifestations of Good's syndrome who succumbed to disseminated tuberculosis. Serum immunoglobulin levels should be measured for patients with thymoma and susceptibility to infection.
