Combined MRI and diffuse-weighted imaging in evaluation of T-staging of gallbladder carcinoma and predicting histological grading
10.3760/cma.j.issn.1007-8118.2019.10.006
- VernacularTitle: 常规MRI结合扩散加权成像评估胆囊癌T分期并判断其组织学分级
- Author:
Lixia QI
1
;
Lan LIN
;
Xu BAI
;
Tao ZHANG
;
Ping YAN
;
Haiyi WANG
;
Huiyi YE
Author Information
1. Department of Radiology, First Medical Center of PLA General Hospital, Beijing 100853, China (Qi Lixia is working in CT-MRI Department of Ordos Central Hospital)
- Publication Type:Journal Article
- Keywords:
Gallbladder neoplasms;
Neoplasm staging;
Magnetic resonance imaging;
Diffusion weighted imaging;
Apparent diffusion coefficient
- From:
Chinese Journal of Hepatobiliary Surgery
2019;25(10):741-745
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study convention MRI compared with conventional MRI combined with diffusion-weighted imaging (DWI) in the evaluation of T-staging of gallbladder carcinoma, and to determine the relationship between the apparent diffusion coefficient (ADC) value and histological grading.
Methods:Fifty-one patients with gallbladder carcinoma confirmed by surgery and pathology were enrolled into this study. The T-staging was performed according to conventional MRI or with conventional MRI combined with DWI and the results were compared with pathological studies.
Results:The ADC value of tumor was measured to determine the correlation with T staging, pTNM staging and pathological tumor differentiation. For conventional MRI, the T-staging rate was 84.3%, which was consistent with the pathological T scoring (Kappa value 0.7580). After DWI, the T staging coincidence rate was 92.2% and the Kappa value was 0.8813. A comparison between conventional MRI versus conventional MRI combined with DWI T-staging compliance rates was performed using the Chi-square test (χ2=1.5111, P>0.05). The ADC values correlated with the T-staging, pTNM staging, and pathological tumor differentiation (r=-0.672, -0.749, 0.707, respectively, all P<0.05).
Conclusions:Conventional MRI helped in the diagnoses of T-staging in gallbladder cancer. MRI combined with DWI helped to improve the coincidence rate of T-staging. The ADC values correlated with the T-staging, pTNM staging, and pathological tumor differentiation. Conventional MRI combined with DWI better evaluated the T-staging of gallbladder cancer, and could better guide the choice of treatment methods.
