Safety and effectiveness of infra-hepatic inferior vena cava clamping combined with Pringle’s maneuver during hepatectomy: a meta-analysis
10.3760/cma.j.issn.1007-8118.2019.10.003
- VernacularTitle: 肝下下腔静脉阻断联合Pringle阻断在肝切除术中安全性及有效性的荟萃分析
- Author:
Xin ZHAO
1
;
Zehua LEI
;
Fengwei GAO
;
Jianping WU
;
Jinqiang FU
;
Bo DU
;
Zhixu WANG
Author Information
1. Department of Hepatopancreaticobiliary Surgery, Le Shan People’s Hospital of Sichuan Province, Leshan 614000, China
- Publication Type:Journal Article
- Keywords:
Hepatectomy;
Infrahepatic inferior vena cava;
Pringle clamping;
Meta-analysis
- From:
Chinese Journal of Hepatobiliary Surgery
2019;25(10):728-732
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the safety and effectiveness of infra-hepatic inferior vena cava clamping combined with Pringle’s maneuver during hepatectomy.
Methods:The databases of PubMed, Cochrane Center, CNKI, VIP, Wan Fang were searched to extract the relevant data for the meta-analysis using the Revmanage 5.3 software.
Results:A total of 14 studies with 1595 patients were included in this meta-analysis. The results showed that total bleeding during the combined clamping was significantly lower than that of the Pringle’s maneuver alone (MD=-314.59, 95%CI: -362.37~-266.81, P<0.05). Bleeding during hepatectomy was significantly lower (MD=-217.79, 95% CI: -284.57~-151.00, P<0.05); so was the intraoperative blood transfusion rate (OR=0.48, 95% CI: 0.36~0.62, P<0.05). The incidence of complications was significantly lower (OR=0.74, 95% CI: 0.57~0.95, P<0.05). However, there were no significant differences in operation time, length of hospital stay, intraoperative monitoring index and postoperative liver and kidney function recovery (P>0.05).
Conclusions:Infra-hepatic inferior vena cava clamping combined with Pringle’s maneuver in hepatectomy was safe and reliable. Compared with the Pringle’s maneuver alone, the combined technique reduce bleeding and the incidence of complications. This technique is worth promoting in clinical practice.