Association between frailty and sleep duration among people aged 50 years and over
10.3760/cma.j.issn.0254-6450.2019.10.015
- VernacularTitle: 50岁及以上人群睡眠时间与衰弱的关联研究
- Author:
Yanfei GUO
1
;
Ye RUAN
1
;
Yize XIAO
2
;
Xiaolei GUO
3
;
Shuangyuan SUN
1
;
Zhezhou HUANG
1
;
Yan SHI
1
;
Fan WU
1
,
4
Author Information
1. Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
2. Yunnan Provincial Center for Disease Control and Prevention, Kunming 650022, China
3. Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China
4. Shanghai Medical College, Fudan University, Shanghai 200032, China
- Publication Type:Journal Article
- Keywords:
Sleep duration;
Frailty
- From:
Chinese Journal of Epidemiology
2019;40(10):1252-1256
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the association between sleep duration and frailty among people aged 50 years and over.
Methods:Cross-sectional data was collected from the first wave of World Health Organization Study on global AGEing and adult health in China. Frailty index was constructed on the proportion of deficits, out of the 40 variables. A two-level (individual level and community level) linear model was performed to identify the related factors on frailty. All the models were stratified by age, gender, residence (urban/rural). Restricted cubic spline was performed to graphically evaluate the dose-response association between self-reported sleep duration and frailty.
Results:A total of 13 175 individuals aged 50 years and over participated in this study. Without adjusting on any confounding factors, shorter or longer sleep duration significantly increased the risk of weakness compared with normal sleep time (OR=2.05, 95%CI: 1.71-2.44; OR=1.35, 95%CI: 1.12-1.63). After adjusting for confounding factors such as gender, age, residence, education, family assets, vegetable, smoking, drinking and physical activity, a positive association between short sleep duration and frailty was noticed compared with normal sleep time (aOR=1.60, 95%CI: 1.27-2.01). The results of stratified analysis on sex, age and urban and rural areas showed that, after adjusting for gender, age, residence, education level, family assets, intake of vegetables and fruits, smoking, drinking and physical activity, only shorter sleep duration was positively correlated with the risk of weakness. In addition, among people aged 65 years and over, adjusted for confounding factors, the risk of weakness increased by 91%, compared with normal sleep time (aOR=1.91, 95%CI: 1.46-2.49). The dose-response curve also showed that the sleep duration and frailty present an approximate "U" shaped relationship.
Conclusion:Short sleep duration might be associated with frailty.
