A Case of Xeroderma Pigmentosum.
- Author:
Sung Choon LIM
;
Song OH
;
Nack In KIM
;
Choong Rim HAW
- Publication Type:Case Report
- MeSH:
Actins;
Biopsy;
Cheilitis;
Child;
Cytochrome P-450 CYP1A1;
Female;
Humans;
Ichthyosis*;
Immune System;
Immunologic Tests;
Lip;
Melanosis;
Photophobia;
Skin Neoplasms;
T-Lymphocytes;
Xeroderma Pigmentosum*
- From:Korean Journal of Dermatology
1985;23(1):59-62
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The role of the immune system in pathogenesis of skin cancer has been attracted increasing attention in recent years. Some limited studies and observations suggest that altered immune status may be a factor in the initiation and growth of cutaneous malignancies. Authors experienced a typical case of xeroderma pigmentosum in a 6 year-old girl, who has been suffered from hyper and hypopigmented macules on sun-exposed area, photophobia and also noted eroded lesion on the lower lip. The biopsy finding of the hyperpigmented macule showed that of freckle and the finding of actinic cheilitis was observed from the specimen of eroded 1esion on the lower lip. We performed immunologic test and obtained some evidences of immunologic defect; such as decreased numbers of total T cells, T-suppressor cell and B cell in our patient.
