Diagnostic value of ultrasound-guided 14 gauge-core needle biopsy in breast nodules
10.3760/cma.j.issn.1007-631X.2019.10.013
- VernacularTitle: 超声引导下14G空心针穿刺活检对乳腺结节的诊断价值
- Author:
Chun ZHANG
1
;
Xue YU
1
;
Yonghui ZHANG
1
;
Fenfen FU
1
;
Dongjie ZHANG
1
;
Lingduo XIE
1
;
Futao CHU
1
;
Chen LI
1
;
Qinqin WANG
1
;
Shuo XU
1
;
Yuntao XIE
1
Author Information
1. Department of Breast Surgery, Peking University International Hospital, Beijing 102206, China
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Biopsy;
Concordance
- From:
Chinese Journal of General Surgery
2019;34(10):867-870
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the diagnostic value of ultrasound guided 14 gauge coreneedle biopsy (US-CNB) in breast nodules.
Methods:We retrospectively analyzed the pathological results of US-CNB and surgical excision from 373 breast nodules in Peking University International Hospital from Sep 2016 to Nov 2018 to evaluate the accuracy of 14g US-CNB.
Results:A total of 349 patients(373 nodules)underwent US-CNB. US-CNB reported 282 benign lesions(75.6%, 282/373), 20 high-risklesions(5.4%, 20/373), and 71 malignant lesions(19.0%, 71/373). For 282 CNB reported benign lesions, the surgical pathology confirmed 235 lesions , 46 for high-risk lesions and 1 for malignant lesion with a concordancy of 83.3%(235/282)and the underestimation rate was 16.7%(47/282). US-CNB identified 20 high-risk lesions. According to surgical results, 15 were high-risk lesions and 5 were malignant lesions with a concordancy of 75% (15/20)and the underestimation rate was 25%(5/20). When it comes to malignant lesions, the excision results showed that 70 were malignant lesions and 1was high-risk lesion with a concordancy of 98.6%(70/71)and the overestimation rate was 1.4%(1/71). The concordance of the histological type , calculated for 50 invasive carcinomas, was 92% (46/50) with a kappa value of 0.77.The concordance of the histological grade could be calculated for 38 invasive ductal carcinomas with the Elston-Elllis Method . It was 89.5% (34/38) with a kappa value of 0.57.
Conclusions:The pathology result of 14gUS-CNB is in good consistency with surgical excision for breast benign and malignant lesions.
