Observation of preliminary efficacy and nursing care of skin relief cream and Biafine for radiation-induced skin damage in patients with nasopharyngeal carcinoma
10.3760/cma.j.issn.1004-4221.2019.10.002
- VernacularTitle: 放肤膏对比比亚芬防治鼻咽癌放射性皮肤损伤的初步疗效观察及护理
- Author:
Kefu SHI
1
;
Liping QI
;
Dan ZHOU
;
Huixia FENG
Author Information
1. Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China
- Publication Type:Journal Article
- Keywords:
Nasopharyngeal neopalsm/ intensity-modulated radiotherapy;
Radiation-induced skin damage;
Nursing
- From:
Chinese Journal of Radiation Oncology
2019;28(10):728-730
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the preliminary efficacy and nursing care of radioprotective agent skin relief cream and Biafine for the prevention and treatment of neck radiation-induced skin damage in patients with nasopharyngeal carcinoma.
Methods:Sixty-seven nasopharyngeal carcinoma patients initially treated with intensity-modulated radiotherapy in Sun Yat-sen University Cancer Prevention and Control Center from 2016 to 2017 were recruited and assigned into the control (n=36) and experimental groups (n=31). In the control group, Biafine was applied to the skin in the radiation field and radioprotective agent skin relief cream was applied in the experimental group. The degree of radiation skin injury and adverse reactions were statistically compared between two groups.
Results:No grade IV radiation-induced skin damage occurred in two groups. The incidence rates of grade 1, 2 and 3 radiation-induced skin damage in the experimental group were 45%, 42% and 13%, and 17%, 64% and 19% in the control group, respectively (P=0.04). Radioprotective agent skin relief cream could control the radiation-induced skin injury within grade Ⅱ and significantly increase the proportion of grade I skin injury.
Conclusion:Medical radioprotective agent is superior to Biafine in the prevention and treatment of radiation-induced skin damage in patients with nasopharyngeal carcinoma.
