Effect of different types of endotracheal tubes on ventilator-associated pneumonia
10.3760/cma.j.issn.1671-0282.2019.10.022
- VernacularTitle: 不同类型气管导管对呼吸机相关性肺炎的影响
- Author:
Ling JIA
1
;
Jiao CHEN
;
Jinghui YANG
;
Xiang XUE
;
Jianqin CAI
;
Wei ZHAO
Author Information
1. Intensive Care Unit, Sir Run Run Hospital, Nanjing Medical University, Nanjing, 211100, China
- Publication Type:Clinical Trail
- Keywords:
Endotracheal tube;
Mechanical ventilation;
Ventilator-associated pneumonia
- From:
Chinese Journal of Emergency Medicine
2019;28(10):1292-1295
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical effect of conventional polyvinyl chloride (PVC) endotracheal tube with silicone wire reinforced endotracheal tube to prevent ventilator-associated pneumonia (VAP) in mechanical ventilation patients.
Methods:A total of 240 mechanical ventilation patients in the ICU were enrolled in this study, which were divided into two groups, PVC endotracheal intubation group (PVC group, n=113) and wire reinforced endotracheal intubation group (WR group, n=127). Gender, age, APACHEⅡ score, one-time success rate of intubation, intubation time, the rate of changing endotracheal, ventilation time, rate of tracheotomy and the incidence of VAP were compare between the two groups. Predictive factors for VAP were identified by the univariate and multivariate analyses in step-wise logistic regression model.
Results:The rate of changing endotracheal tube in the PVC group was lower than that in the WR group (χ2=5.785, P=0.016); the mechanical ventilation time in the PVC group was shorter than that in the WR group (t=2.180, P=0.018); and compared with the WR group, the PVC group had significantly lower incidence of VAP (χ2=6.215, P=0.012). The univariate analysis showed that the selection of PVC endotracheal tube, APACHE Ⅱ score and mechanical ventilation time were the significant risk factors for VAP (P < 0.05). Multivariate analysis showed that the different selection of endotracheal tube and mechanical ventilation time were independent influencing factors of VAP (P < 0.05).
Conclusions:PVC tracheal tube can effectively reduce the incidence of VAP in patients with mechanical ventilation.
