Clinical observation of 43 cases of acute poisoning caused by herbicide marked diquat
10.3760/cma.j.issn.1671-0282.2019.10.021
- VernacularTitle: 43例成份标注为敌草快的除草剂急性中毒临床观察
- Author:
Yuxuan WU
1
;
Jinsong ZHANG
1
;
Li QIAO
1
;
Hao SUN
1
;
Jianrong CHEN
2
;
Lijun LIU
3
;
Jiyang XU
4
;
Hong SUN
5
;
Yeping DU
6
;
Zhiguang TIAN
7
;
Rushan YANG
8
Author Information
1. Department of Emergency, the First Affilicated Hospital of Nanjing Medical University, Nanjing 210029, China
2. Department of Emergency Department , the First People's Hospital of Nantong City, Nantong, 226001, China
3. Department of Emergency, the Second Affiliated Hospital of Suzhou University, Suzhou, 215008, China
4. Department of Emergency, Subei People’s Hospital, Yangzhou, 225001, China
5. Department of Emergency, the Fisrt People’s Hospital of Huai’an city, Huai’an, 223300, China
6. Department of Emergency, the Second People’s Hospital of Huai’an city, Huai’an, 223002, China
7. Department of Emergency , the Third People’s Hospital of Xuzhou city, Xuzhou, 221005, China
8. Department of Emergency, the People’s Hospital of Rugao city, Rugao, 226005, China
- Publication Type:Clinical Trail
- Keywords:
Diquat;
Herbicide;
Acute poisoning;
Multi-center;
Retrospective study
- From:
Chinese Journal of Emergency Medicine
2019;28(10):1287-1291
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the relationship between clinical characteristics and prognosis of patients with acute herbicide poisoning marked diquat.
Methods:A multi-center, retrospective clinical study of patients with acute diquat poisoning admitted into Emergency Department was conducted from June 2015 to August 2018 in 8 hospitals in Jiangsu Province.
Results:A total of 43 patients (22 males and 21 females) were collected and the peak age of poisoning ranged 20-39 years old. The only route of poisoning was ingestion. Among these cases, suicide was the most common cause of poisoningaccounting for 90.70%. In emergency treatment, the constituent ratios of gastric lavage, hemoperfusion and glucocorticoid were 87.50%, 72.50% and 42.50%, respectively. The total mortality increased to 60.00% after follow-up, while the in-hospital mortality was 18.60%. The mortality of patients with toxic dose < 50 mL was 11.11%.
Conclusions:The incidence of acute herbicide poisoning with "diquat" as commercial component is gradually increasing. At present, the mortality is very high. Ingestion poisoning dose is the key factor affecting prognosis, and the prognosis of patients with oral dose > 50 mL is poor.
