Advance in Zika virus infection-related myelitis
10.3760/cma.j.issn.0254-5101.2019.10.013
- VernacularTitle: 寨卡病毒感染相关脊髓炎研究进展
- Author:
Gen MIAO
1
;
Cuiling DING
1
;
Yangang LIU
1
;
Zhongtian QI
1
Author Information
1. Department of Microbiology, Faculty of Naval Medicine, Shanghai Key Laboratory of Medical Biodefense, the Second Military Medical University, Shanghai 200433, China
- Publication Type:Review
- Keywords:
Zika virus;
Myelitis;
Pathogenic mechanism
- From:
Chinese Journal of Microbiology and Immunology
2019;39(10):800-804
- CountryChina
- Language:Chinese
-
Abstract:
Zika virus belongs to the family Flaviviridae, genus Flavivirus and is mainly transmitted to humans by Aedes. The outbreak of Zika virus infection in South America in 2015 raised worldwide health concern due to the increasing incidence of microcephaly, Guillain-Barre syndrome and myelitis, although most of the patients were asymptomatic. Here, to further understand and elucidate the pathogenic mechanism of Zika virus infection-associated myelitis, this review summarized the latest advance in biological characteristics, transmission and treatment of Zika virus infection as well as the related case reports and possible mechanisms.