Association between gastrointestinal problems and symptoms in children with autism spectrum disorders
10.3760/cma.j.issn.2095-428X.2019.10.011
- VernacularTitle: 孤独症谱系障碍患儿胃肠问题与症状表现关联研究
- Author:
Ke LI
1
,
2
;
Yiting JI
1
,
2
;
Xiaodong JIANG
3
;
Fei LI
4
,
5
Author Information
1. Department of Developmental Behavioral Pediatrics, Shanghai Children′s Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
2. MOE-Shanghai Key Laboratory of Children′s Environmental Health, Shanghai 200092, China
3. Department of Children Healthcare, Children′s Hospital of Chongqing Medical University, Chongqing 400014, China
4. MOE-Shanghai Key Laboratory of Children′s Environmental Health, Shanghai 200092, China
5. Department of Developmental Behavioral Pediatrics and Children Healthcare, Shanghai Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
- Publication Type:Journal Article
- Keywords:
Autism spectrum disorder;
Gastrointestinal problems;
Sensory over reponsitivity;
Emotional problems
- From:
Chinese Journal of Applied Clinical Pediatrics
2019;34(10):768-772
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the association between gastrointestinal problems and autism spectrum disorders(ASD) related symptoms, in order to give some clues to the management of ASD children.
Methods:Three hundred and thirty-six ASD children aged from 3-8 years old were recruited for the study according to the inclusion and exclusion criteria.General information about the children, including birth date, gender, food allergy history, gastrointestinal problems in the recent 3 months and social psychological scales, were completed by parents or caretakers.The association between gastrointestinal problems and ASD related symptoms (repetitive and stereotypic behaviors, sensory processing problems, emotional and behavioral problems) were analyzed.
Results:Among 336 ASD individuals, gastrointestinal problems were detected in 85 children.General gastrointestinal problem detection rate was 25.3%.ASD children with gastrointestinal problems were more severe in sensory over responsitivity(t=3.172, P<0.05), as well as emotional problems(t=-3.215, P<0.05). According to the regression analysis, gastrointestinal problem was significantly associated with sensory over responsitivity[β(SE)=-0.041, P<0.05, Exp(β)=-0.959], as well as emotional problems[β(SE)=0.375, P<0.05, Exp(β)=1.456]. Specifically, vomit was significantly associated with sensory over responsitivity(B=-14.446, P<0.05), and constipation was significantly associated with emotional problems(B=1.555, P<0.05).
Conclusions:Gastrointestinal problems are often seen in Chinese ASD children.Gas-trointestinal problems are significantly associated with sensory over responsitivity, as well as emotional problems, implying that resolving gastrointestinal problems may be helpful to remit these problems.
