Risk Factors for Death during Pulmonary Tuberculosis Treatment in Korea: A Multicenter Retrospective Cohort Study.
10.3346/jkms.2014.29.9.1226
- Author:
Yong Soo KWON
1
;
Yee Hyung KIM
;
Jae Uk SONG
;
Kyeongman JEON
;
Junwhi SONG
;
Yon Ju RYU
;
Jae Chol CHOI
;
Ho Cheol KIM
;
Won Jung KOH
Author Information
1. Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea.
- Publication Type:Original Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
- Keywords:
Tuberculosis, Pulmonary;
Therapeutics;
Mortality, Korea
- MeSH:
Adult;
Aged;
Anemia/complications;
Antitubercular Agents/*therapeutic use;
Cohort Studies;
Dyspnea/complications;
Female;
Heart Diseases/complications;
Humans;
Intensive Care Units;
Male;
Middle Aged;
Multivariate Analysis;
Neoplasms/complications;
Prognosis;
Republic of Korea;
Retrospective Studies;
Risk Factors;
Sex Factors;
Treatment Outcome;
Tuberculosis/complications/*drug therapy/mortality
- From:Journal of Korean Medical Science
2014;29(9):1226-1231
- CountryRepublic of Korea
- Language:English
-
Abstract:
The data regarding risk factors for death during tuberculosis (TB) treatment are inconsistent, and few studies examined this issue in Korea. The purpose of this study was to evaluate baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea. A multicenter retrospective cohort study of 2,481 patients who received TB treatment at eight hospitals from January 2009 to December 2010 was performed. Successful treatment included cure (1,129, 45.5%) and treatment completion (1,204, 48.5%) in 2,333 patients (94.0%). Unsuccessful treatment included death (85, 3.4%) and treatment failure (63, 2.5%) occurred in 148 patients (6.0%). In multivariate analysis, male sex, anemia, dyspnea, chronic heart disease, malignancy, and intensive care unit (ICU) admission were significant risk factors for death during TB treatment. Therefore, male sex, anemia, dyspnea, chronic heart disease, malignancy, and ICU admission could be baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea.
