Progress in diagnosis and treatment of restless legs syndrome
10.3760/cma.j.issn.1671-7368.2019.10.018
- VernacularTitle: 不宁腿综合征的诊断与治疗进展
- Author:
Caixia YAO
1
;
Liuqing WANG
2
;
Shoucheng ZHANG
2
Author Information
1. Department of Endocrinology, Gaochun Pepole′s Hospital, Nanjing 211300, China
2. Department of Neurology, Gaochun Pepole′s Hospital, Nanjing 211300, China
- Publication Type:Review
- Keywords:
Restless legs syndrome;
Sleeping disorder;
Dopa;
Iron
- From:
Chinese Journal of General Practitioners
2019;18(10):994-997
- CountryChina
- Language:Chinese
-
Abstract:
Restless legs syndrome (RLS) is defined as a sleep-wake disorder, with the key feature being an urge to move, which can be classified as two types as primary RLS and secondary RLS. Iron deficiency is a key role of RLS, low levels of serum ferritin is noted in RLS lab tests. Pathophysiology of RLS is complex, genetic variants, anatomical network vulnerability, neurotransmission abnormalities and abnormal dopaminergic neurotransmission may all contribute to its pathogenesis. The mild RLS can choose non-drug therapy, but most of the patients need drug therapy especially the severe cases. The aboved aspects are discussed in this review based on recent literatures.
