Preoperative Embolization of Extra-axial Hypervascular Tumors with Onyx.
10.7461/jcen.2016.18.1.12
- Author:
Matthew R FUSCO
1
;
Mohamed M SALEM
;
Bradley A GROSS
;
Arra S REDDY
;
Christopher S OGILVY
;
Ekkehard M KASPER
;
Ajith J THOMAS
Author Information
1. Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
- Publication Type:Original Article
- Keywords:
Embolization;
Endovascular;
Meningioma;
Onyx;
Tumor
- MeSH:
Hemangiopericytoma;
Humans;
Meningioma;
Polyvinyl Alcohol
- From:Journal of Cerebrovascular and Endovascular Neurosurgery
2016;18(1):12-18
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: Preoperative endovascular embolization of intracranial tumors is performed to mitigate anticipated intraoperative blood loss. Although the usage of a wide array of embolic agents, particularly polyvinyl alcohol (PVA), has been described for a variety of tumors, literature detailing the efficacy, safety and complication rates for the usage of Onyx is relatively sparse. MATERIALS AND METHODS: We reviewed our single institutional experience with pre-surgical Onyx embolization of extra-axial tumors to evaluate its efficacy and safety and highlight nuances of individualized cases. RESULTS: Five patients underwent pre-surgical Onyx embolization of large or giant extra-axial tumors within 24 hours of surgical resection. Four patients harbored falcine or convexity meningiomas (grade I in 2 patients, grade II in 1 patient and grade III in one patient), and one patient had a grade II hemangiopericytoma. Embolization proceeded uneventfully in all cases and there were no complications. CONCLUSION: This series augments the expanding literature confirming the safety and efficacy of Onyx in the preoperative embolization of extra-axial tumors, underscoring its advantage of being able to attain extensive devascularization via only one supplying pedicle.
