Long-Term Outcomes of Acute Ischemic Stroke in Patients Aged 80 Years and Older.
10.3349/ymj.2008.49.3.400
- Author:
Yang Ki MINN
1
;
Soo Jin CHO
;
Seon Gyeong KIM
;
Ki Han KWON
;
Jin Hyuck KIM
;
Mi Sun OH
;
Min Kyung CHU
;
Ju Hun LEE
;
Sung Hee HWANG
;
Byung Chul LEE
Author Information
1. Department of Neurology, 1Hangang Sacred Heart Hospital, Seoul, Korea. dowonc@naver.com
- Publication Type:Original Article
- Keywords:
Aging;
ischemic stroke;
prognosis;
mortality
- MeSH:
Age Factors;
Aged, 80 and over;
Brain Ischemia/mortality/*pathology;
Female;
Humans;
Kaplan-Meiers Estimate;
Male;
Prognosis;
Stroke/mortality/*pathology;
Survival Rate;
Time Factors
- From:Yonsei Medical Journal
2008;49(3):400-404
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Short life expectancy influences decision-making when treating very old patients with acute ischemic stroke (AIS). We investigated mortality and survival duration in very old AIS patients (> or =80 years) who received hospital care. PATIENTS AND METHODS: Mortality data were obtained from medical records, structured telephone inquiries, death certificates from the Korean National Statistical Office, and social security data 5+/-1.9 years after stroke onset. Age, gender, vascular risk factors, and functional outcomes from modified Rankin scales (MRS) at discharge were analyzed as predictors of mortality. RESULTS: Among 134 patients, 92 (68.7%) died. On Kaplan- Meier analysis, duration of survival of patients aged 80-84 years was longer than those aged 85-89 or 90-94 (24+/-6.4, 8+/-7.3, 7+/-2.0 months, respectively, p=0.002). Duration of survival of patients discharged in a state of MRS 0-1 was longer than the remaining groups at 47+/-4.8 months (p<0.001). In Cox proportional hazard analysis, age and MRS at discharge were independent predictors of mortality. CONCLUSION: Long-term outcomes of very old patients with AIS are not uniformly grave, therefore predictors of mortality and estimated duration of survival should be considered during decision- making for treatment.
