Study on the levels and risk factors of Vitamin D from preconception to pregnancy
10.16462/j.cnki.zhjbkz.2020.01.009
- Author:
Yu ZHANG
1
;
Chang-qian WU
;
Xiao-ying MA
;
Xue-na LA
;
Yan ZHANG
;
Hong-fang MAO
;
Xu-shan CAI
;
Shou-le WU
;
Dong-xiao YIN
;
Hong JIANG
Author Information
1. Department of Maternal, Child and Adolescent Health, School of Public Health, NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai 200032, China
- Publication Type:Research Article
- Keywords:
Preconception;
Pregnant women;
Vitamin D;
Vitamin D deficiency
- From:
Chinese Journal of Disease Control & Prevention
2020;24(1):41-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the levels of serum Vitamin D(VD) from preconception to pregnancy in Jiading district of Shanghai, and explore the risk factors of VD concentration deficiency in the second and third trimester of pregnancy. Methods A total of 94 women who planned to have antenatal care and delivery in Maternal and Child Health Hospital of Jiading district of Shanghai from September 2016 to December 2018 were recruited as the study participants. Chemiluminescent immunoassay (CLIA) was used to examine the concentration of women’s serum VD from preconception to pregnancy. A total of 282 serum samples were detected. Results The prevalence of VD deficiency among 94 women from preconception to pregnancy were 40.4%,57.4% and 48.9% respectively. Results of the mixed linear model showed that women who had dyed or permed hair within the past 1 year had significantly lower serum VD levels during pregnancy (P<0.05), and women who often drank milk and ate deep-sea fish during pregnancy had higher VD levels during pregnancy (P<0.05). Conclusions VD deficiency was common among women in Jiading district of Shanghai, and it should be emphasized to supplement VD before and during pregnancy.