Research progress on the mechanism of miRNA-296 in carcinogenesis and its clinical appliation
10.3872/j.issn.1007-385x.2019.12.019
- VernacularTitle:miRNA-29b在癌症发生发展中的作用机制及其临床应用的研究进展
- Author:
TANG Jinzhou
1
;
MAO Aihong
2
;
LIAO Shiqi
2
Author Information
1. Gansu Academy of Medical Sciences, School of Life Sciences, School of Life Sciences, Lanzhou University
2. Gansu Academy of Medical Sciences
- Publication Type:Review
- Keywords:
miR-29b;癌症;调控机制;临床转化
- From:
Chinese Journal of Cancer Biotherapy
2019;26(12):1410-1416
- CountryChina
- Language:Chinese
-
Abstract:
miR-29b是最近生物医学界所关注的研究热点之一,尤其在人类癌症中。越来越多的研究发现,miR-29b在多种癌症 中异常表达,与肿瘤细胞增殖、分化、凋亡、侵袭、转移及药物耐受相关,有望成为癌症的新型诊断标志物及治疗靶点。本文重点 就miR-29b在人类癌症中的表达、作用及其调控机制和临床应用的研究进展进行综述,以促进miR-29b在临床诊断和治疗中的转 化应用。
- Full text:20191219.pdf