Enteral nutrition treatment on nutritional status of patients with esophageal cancer during radiotherapy in Chinese population: a meta-analysis
10.19485/j.cnki.issn2096-5087.2018.02.011
- VernacularTitle:肠内营养治疗对改善中国食管癌放疗患者营养状况的Meta分析
- Author:
En-Yi QIU
1
;
Xi-Yue ZHAO
;
Zhang JIN
;
Quan-Bing LIN
Author Information
1. 温州市中心医院
- Keywords:
Esophageal cancer;
Enteral nutrition;
Radiotherapy;
Nutritional status;
Meta analysis.
- From:
Journal of Preventive Medicine
2018;30(2):153-157
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate enteral nutrition treatment on nutritional status of patients with esophageal cancer during radiotherapy in Chinese population. Methods We searched domestic and foreign relevant databases (PubMed, Medline, Cochrane Library, Wanfang Data, Chinese Journal Database, VMIS) by key words (esophageal cancer, chemoradiotherapy, enteral nutrition) , meeting the conditions of the clinical randomized controlled trials, and evaluated the quality of each document. We used meta-analysis method to analysis the published literatures about clinical randomized controlled trials, which were enteral nutrition treatment on nutritional status of patients with esophageal cancer during radiotherapy in Chinese population.RevMan5.1 statistical analysis software were used. Results Seven separate clinical randomized controlled trials including 503 cases were included into the meta-analysis. The following five indexes of nutritional status in enteral nutrition treatment (ENT) group were superior to routine treatment (RT) group (P<0.05): body weight, Body Mass Index (BMI), hemoglobin, serum albumin, serum prealbumin. The MD Values and 95％CI (confidence interval) were 5.54 (3.61-7.46), 2.20 (2.02-2.39), 12.46 (5.86-19.05), 4.04 (2.48-5.61), 49.53 (20.93-78.13) .The funnel plot showed no significant publication bias in each indexes. Conclusion Enteral nutrition treatment can improve the nutritional status of patients with esophageal cancer during radiotherapy compare only with routine treatment.
