Prognostic factors affecting survival of 211 cervical adenocarcinoma patients
10.19485/j.cnki.issn1007-0931.2017.04.009
- VernacularTitle:211例宫颈腺癌治疗患者生存预后影响因素分析
- Author:
Xiao-Xian XU
1
;
Xiao-Jing ZHANG
;
Jian-Song ZHOU
;
Han-Mei LOU
Author Information
1. 浙江省肿瘤医院妇科
- Keywords:
Cervicalcancer;
Adenocarcinoma;
Survival rate;
Prognostic factor
- From:
Journal of Preventive Medicine
2017;29(4):360-362
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study was conducted to determine the prognostic factors of cervical adenocarcinoma.Methods Between July 2008 and June 2013, 211 consecutive patients were treated because of International Federation of Gynecology and Obstetrics(FIGO) stage IA-IVB cervical adenocarcinoma.Overall survival was analyzed by the Kaplan-Meier method.Results One-year OS rate was 96.2%,and 3-year OS rate was 88.6%,and 5-year OS rate was 74.7%.Patients'age,FIGO stage,postoperative clinicopathological factors such as depth of stromal invasion,number of pelvic lymph node metastasis and para-aortic lymph node metastasis,were analyzed to discriminate their prognostic role.In the univariate analysis, age,FIGO stge,deep stromal invasion, lymph-vascular space invasion, number of pelvic lymph node metastasis,para-aortic lymph node metastasis were associated with poorer survival(P< 0.05).In the cox analysis, age (RR=4.940,95%CI:1.925-12.678),pelvic lymph node metastasis(RR=2.391,95%CI:1.311-4.360),para-aortic lymph node metastasis (RR=6.344,95%CI:1.007-39.990)and FIGO stage(Ⅲ vs I,RR=5.315,95%CI:2.760-12.203;Ⅳ vs I,RR=9.932,95%CI:2.905-18.846)were independent prognostic factors of invasive cervical adenocarcinoma.Conclusion Early detection and early treatment is very important for cervical adenocarcinoma patients.Give the patient suitable and maybe more aggressive adjuvant therapy according to surgical pathology is helpful for imporving adenocarcinoma treatment.
