An assessment of the relationship between bone loss and carbonated beverages: a meta-analysis

VernacularTitle:碳酸饮料与骨丢失关系的Meta分析
Author: Yan ZOU ¹ ; Dan LI ; Jia MENG ; Li-Chun HUANG ; Yue-Qiang FANG ; Rong-Hua ZHANG
Author Information

1. 浙江省疾病预防控制中心
Keywords: Carbonated beverages; Bone density; Fracture; Meta-analysis
From: Journal of Preventive Medicine 2017;29(3):221-225
CountryChina
Language:Chinese
Abstract: Objective The aim of the present study was to estimate the quantitative contributions of carbonated beverages consumption to bone loss.Methods We pedormed computer searches of PubMed,Cochrane Library,EBSCO,CALIS to search for studies investigating the relationship between carbonated beverages and bone loss.For carbonated beverages investigated in a comparative way,we use random effect model to compute pooled odds ratios (ORs) and Cochran Q statistic to estimate the heterogeneity.Results A total of 10 studies met the inclusion criteria and the relationships between carbonated beverages and bone loss were considered,including colas and bone loss.The following associations were found for carbonated beverages and low bone density (OR =1.28,95％ CI =1.02-1.60),carbonated beverages and bone fractures (OR =1.53,95％ CI =1.04-2.26),colas and bone fractures (OR =2.00,95％ CI =1.24-3.24).Condusion The present results indicate that carbonated beverages were associated with bone loss.This meta-analysis may have important public health implications given the widespread use of carbonated beverages.