N-acetyl Transferase 2 Gene Polymorphisms in Patients with Endometriosis.
- Author:
Young Min CHOI
1
;
Ji Sung YOON
;
Seung Yup KU
;
Kyu Sup LEE
;
Sung Hyo PARK
;
Eun Ran CHANG
;
Noh Hyun PARK
;
In Ae PARK
;
Jong Kwan JUN
;
Chang Suk SUH
;
Seok Hyun KIM
;
Jung Gu KIM
;
Shin Yong MOON
Author Information
1. Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Endometriosis;
N-acetyl transferase 2;
NAT 2 gene;
Polymorphism
- MeSH:
Endometriosis*;
Female;
Genotype;
Humans;
Laparoscopy;
Laparotomy;
Transferases*
- From:Korean Journal of Obstetrics and Gynecology
2003;46(11):2113-2117
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To explore the association of the N-acetyl transferase 2 (NAT 2) gene polymorphisms with endometriosis. METHODS: One hundred seventy-two women with surgically or histologically diagnosed endometriosis of stages I-IV, and 205 patients with no evidence of endometriosis by laparoscopy or laparotomy served as control. Genotype distribution of NAT 2 polymorphisms and frequencies of slow and fast acetylators in affected women and controls were evaluated. RESULTS: There was no statistically significant difference in the genotype distribution of NAT 2 polymorphisms and frequencies of slow and fast acetylators between the patients with endometriosis and the controls. CONCLUSION: These results suggest that N-acetyl transferase 2 gene polymorphisms is not associated with the risk for endometriosis in the Korean population.
