A study on the relationship between serum fatty acids and blood pressure among hypertension patients
- VernacularTitle:高血压患者血清脂肪酸与血压的相关性研究
- Author:
Fang DING
1
;
Feng-Lei WANG
;
Bo YANG
;
Xiao-Lin XU
;
Duo LI
;
Wei YU
Author Information
1. 浙江医院浙江省心脑血管病防治研究中心
- Keywords:
Hypertension;
Serum fatty acids;
Relationship;
α-linolenic acid
- From:
Journal of Preventive Medicine
2015;(6):551-555
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between serum fatty acids and blood pressure among hypertension patients.Methods A total of 93 primary hypertension patients were recruited.Serum fatty acids were determined with capillary gas chromatography.Results There was a statistically significant difference in serum fatty acids composition between male and female patients.Serum compositions of C20:5n -3(4.68% ±1 .36% vs.4.01 % ±1 .22%),C22:6n -3(2.03% ±0.73% vs.1 .62% ±0.54%),total n -3 polyunsaturated fatty acids(8.1 3% ±1 .87% vs.7.08% ± 1 .43%),C20:4n -6(6.1 3% ±1 .66% vs.5.31 % ±1 .25%)and n -3 to n -6 ratio (0.24% ±0.07% vs.0.20% ± 0.05%)among males were significantly higher than that of females,while C1 8:3n -6 (0.45% ±0.1 7% vs.0.58% ± 0.29%)and C20:3n -6 (1 .39% ±0.29% vs.1 .60% ±0.49%)compositions in serum were significantly lower in males.Serum composition of C1 8:3n -3 was significantly negatively correlated to systolic blood pressure (r =-0.23,P =0.03)and pulse pressure (r =-0.23,P =0.03).Conclusion Increased serum composition of C1 8:3n -3 is associated with decreased systolic and pulse pressure.
