A study on the level of N -terminal pro -B -type natriuretic peptide in evaluating the cardiac function of pregnant women with cardiac disease
- VernacularTitle:N末端B型钠尿肽前体水平评价合并心脏病孕妇的心功能研究
- Author:
Fang ZHOU
1
;
Li-Ping CHEN
;
Mei-Fen WENG
;
Jin-Xiang JIANG
Author Information
1. 丽水市妇幼保健院
- Keywords:
N -terminal pro -B -type natriuretic peptide;
Cardiac function;
Pregnant women;
Evaluation
- From:
Journal of Preventive Medicine
2015;(4):351-354
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the cardiac function of pregnant women with cardiac disease and the level of N -terminal pro -B -type natriuretic peptide (NT -pro -BNP).Methods A total of 74 pregnant women with cardiac disease and 80 healthy pregnant women were enrolled in the study and the NT -pro -BNP was detected and compared.The concentrations of NT -pro -BNP in different trimester were compared among the healthy pregnant women, and the correlation between the cardiac function of pregnant women with cardiac disease and the level of NT -pro -BNP were analyzed.Results The median of concentrations of plasma NT -pro -BNP in pregnant women with cardiac disease was 352.50 pg/mL,which was significantly higher than that in healthy pregnant women 58.00 pg/mL(P <0.01 ).The cardiac function was positively correlated with the level of NT -pro -BNP (P <0.01 ).The concentration of plasma NT -pro -BNP during the late trimester(49.00 pg/mL)was significantly higher than that of the early trimester(49.00 pg/mL) among the healthy pregnant women (P <0.01 ).Conclusion It is of great clinical value for the concentration of plasma NT-pro -BNP in evaluating the cardiac function of pregnant women with cardiac disease,and the pregnancy may influence the cardiac function.
