The comparison of macular blood flow parameters in myopic choroidal neovascularization, high myopia and normal people
10.3760/cma.j.issn.1005-1015.2019.05.005
- VernacularTitle:高度近视继发脉络膜新生血管和单纯高度近视患眼以及正常眼黄斑区血流参数 对比观察
- Author:
Yirun SHAO
1
;
Jianbo MAO
;
Lijun SHEN
;
Caiyun ZHANG
;
Yiqi CHEN
;
Zhaokai XU
;
Zicheng ZHENG
;
Jimeng LAO
;
Bowen LIU
Author Information
1. 温州医科大学附属眼视光医院杭州院区 310020
- Keywords:
Myopia,degenerative;
Choroidal neovascularization;
Regional blood flow
- From:
Chinese Journal of Ocular Fundus Diseases
2019;35(5):446-450
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compared the macular blood flow parameters among myopic choroidal neovascularization (mCNV), high myopia (HM) and normal subjects.Methods Retrospective study. Forty patients (40 eyes) diagnosed as mCNV (mCNV group) in the Eye Hospital of Wenzhou Medical University at Hangzhou from June 2016 to November 2018, age-matched, sex-matched and diopter-matched 40 HM patients (40 eyes, HM group), age-matched and sex-matched 40 healthy persons (40 eyes, normal group) were enrolled in this study. Retina superficial and deep vessel density, the area of foveal avascular zone (FAZ), a-circularity index (AI) and vessel density around the 300 μm width of the FAZ region (FD) on macular 3 mm×3 mm scan on OCTA of 3 groups were compared.Results There were significant differences in the average retina superficial, deep vessel density, the area of FAZ, AI and FD among 3 groups (F=24.82, 9.18, 3.58, 7.68, 14.15;P<0.05). The average retina superficial and deep vessel density and FD in mCNV group were lower than those in HM group (P<0.05). The average retina superficial and deep vessel density and FD in HM group were lower than those in control group (P<0.05). The average area of FAZ in mCNV group was smaller than that in control group (P<0.05). The average AI in mCNV group was less than that in the other 2 groups (P<0.05). Conclusions The retina superficial, deep vessel density and FD decreased, the area and the form of FAZ remained unchanged in HM subjects comparing with normal subjects. While retina superficial, deep vessel density and FD decreased more, the area of FAZ reduced, the form of FAZ tend to be irregular in mCNV.
