Management of acute pancreatitis after kidney transplantation:our experiences of 12 patients
10.3760/cma.j.issn.0254-1785.2019.08.009
- VernacularTitle:肾移植术后急性胰腺炎12例诊治经验
- Author:
Huijun REN
1
;
Wenjun SHANG
;
Xiaohan MA
;
Yong CUI
;
Liang MING
Author Information
1. 郑州大学第一附属医院检验科
- Keywords:
Kidney transplantation;
Complication;
Acute pancreatitis;
Immunosuppressant
- From:
Chinese Journal of Organ Transplantation
2019;40(8):489-491
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the experiences of diagnosing and treating acute pancreatitis (AP) after kidney transplantation .Methods From September 2007 to December 2017 , clinical data were retrospectively analyzed for 12 AP patients after kidney transplantation .Results They were diagnosed as AP within 72 h after an onset of abdominal pain .Among 4 recurrent cases within 1 week post-transplantation ,the curative interventions included non-operative therapy (n=2) and peripancreatic puncture & drainage (n=2) .AP occurred at 1 year post-transplantation (n=8) . Three cases were cured non-surgically while another 5 cases underwent surgery . The procedures included laparoscopic cholecystectomy ( n = 1 ) , endoscopic retrograde cholangiopancreatography (ERCP) for cholelithiasis (n=1) and peripancreatic puncture & drainage (n= 2) .One patient died after surgical debridement for adjacent pancreatic tissue .Conclusions After kidney transplantation , the occurrence of AP may be associated with immunosuppressants interfering with triglyceride metabolism and pancreatic microcirculation .For those with cholelithiasis-related pancreatitis ,surgical removal of precipitating factor is required .Mini-invasive puncture and drainage are preferred for severe non-gallstone pancreatitis while surgery is performed whenever necessary .
