Therapeutic effect of anterior approach combined with liver hanging maneuver for right hepatectomy in patients with large hepatocellular carcinoma
10.3760/cma.j.issn.1007-631X.2019.09.012
- VernacularTitle:前入路联合悬吊法切除右肝大肝癌的疗效分析
- Author:
Jun WU
1
;
Kai YIN
;
Jianwei XU
;
Lide TAO
;
Lihong ZHANG
Author Information
1. 扬州大学附属泰兴市人民医院肝胆外科
- Keywords:
Carcinoma,hepatocellular;
Hepatectomy;
Outcome assessment
- From:
Chinese Journal of General Surgery
2019;34(9):787-790
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate hepatectomy by anterior approach combined with liver hanging maneuver against conventional right hepatectomy in patients with large hepatocellular carcinoma (HCC).Methods Of the 62 cases,29 patients underwent anterior approach hepatectomy and 33 did conventional hepatectomy.Results The overall operative time (t =1.815,P =0.037) and parenchymal transsection time (t =4.591,P=0.000) were longer in the anterior approach group than in the conventional group.More cases got radical resection in the anterior group (x2 =7.280,P =0.007).Log-rank test showed that 1,3 and 5-year overall survival rate (OS) in the anterior approach group and the conventional group was 86.1%,50.1%,32.6% vs 75.8%,30.3%,18.9%,respectively (x2 =5.24,P=0.022),1,3 and 5-year disease free survival rate (DFS) were 75.3%,42.1%,31.0% vs 66.1%,24.4%,10.1%,respectively (x2 =4.38,P =0.037),and recurrence rate were 23.6%,49.5%,64.8% vs 36.7%,63.7%,82.5%,respectively (x2 =5.61,P =0.018).Conclusion Long term survival of patients with large sized HCC undergoing hepatectomy through the anterior approach combined with liver hanging maneuver is better than that of conventional approach.