Efficacy of lumbar sympathetic ganglion pulsed radiofrequency in treatment of diabetic neuropathic pain
10.3760/cma.j.issn.0254-1416.2019.07.019
- VernacularTitle:腰交感神经节脉冲射频术对糖尿病神经痛的疗效
- Author:
Xiang HUANG
1
;
Hanbing WANG
;
Xiaohong LI
;
Dacheng TANG
;
Pan CHEN
Author Information
1. 佛山市第一人民医院麻醉科 528000
- Keywords:
Ganglia,sympathetic;
Pulsed radiofrequency treatment;
Diabetic neuropathies
- From:
Chinese Journal of Anesthesiology
2019;39(7):844-847
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of lumbar sympathetic ganglion pulsed radiofrequency (PRF) in treatment of diabetic neuropathic pain.Methods Forty-eight patients of both sexes with diabetic neuropathic pain,aged 45-75 yr,with the course of disease 4-7 yr,were divided into 2 groups (n =24 each) using a random number table method:control group (C group) and PRF group (P group).Group C was treated with conventional drugs.Bilateral lumbar sympathetic ganglion PRF was performed on the basis of conventional drug therapy in group P.The serum concentrations of tumor necrosis factor-alpha and interleukin-6 were measured by enzyme-linked immunosorbent assay.The visual analogue scale score was recorded before treatment and at 1,2 and 4 weeks of treatment.The degree of efficacy was recorded at 4 weeks of treatment,and the total effective rate was calculated.Results Compared with group C,the visual analogue scale score and serum concentrations of tumor necrosis factor-alpha and interleukin-6 were significantly decreased,and the total effective rate and degree of curative efficacy were increased in group P (P＜0.05).No pulsed radiofrequency-related complications or drugs-related adverse reactions were found in two groups.Conclusion Lumbar sympathetic ganglion PRF can effectively relieve diabetic neuropathic pain in the patients.
