The value of contrast‐enhanced ultrasonography in differential diagnosis of orbit tumors in extraconal compartment
10.3760/cma.j.issn.1004‐4477.2019.09.012
- VernacularTitle:超声造影定量参数对眼眶肌锥外间隙良恶性肿瘤的鉴别价值
- Author:
Yao ZHANG
1
;
Wenwei CHEN
;
Wei HU
;
Bin SUN
;
Qing DENG
;
Xin HUANG
;
Xingyue HUANG
;
Jun ZHANG
;
Shang WANG
Author Information
1. 武汉大学人民医院超声影像科430060
- Keywords:
Contrast‐enhanced ultrasonography;
Orbit tumors in extraconal compartment;
Time‐intensity curve;
Dynamic vascular pattern
- From:
Chinese Journal of Ultrasonography
2019;28(9):798-802
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide a reference for differential diagnosis of orbit tumors in extraconal compartment by analyzing the parameters of contrast‐enhanced ultrasonography ( CEUS) . Methods A total of 76 patients with orbit tumors in extraconal compartment w ho underwent CEUS examination were retrospectively analyzed . T hese patients were divided into two groups depending on histological diagnosis including 27 cases with malignant tumor and 49 cases with benign tumor . CEUS images were analyzed using Sonoliver software . T he time‐intensity curve ( T IC ) and dynamic vascular pattern curve ( DVPC ) were acquired and the characteristics of the arterial flow infusion of these were analyzed . T he related parameters such as time of arrival time( AT ) ,rise time ( RT ) ,time to peak( T T P) ,mean transit time( mT T ) ,slope of rise( K1 ) ,the absolute value for slope of down ( K 2 ) were also obtained . T he differences of DVPC ,TIC and quantitative parameters between the two groups were compared . Receiver operating curve analysis was used to acquire the cut‐off values of these parameters for differential diagnosis . Results ① T ICs of the benign tumors were mainly fast rise and slow drop and DVPCs were mainly positive biphasic ,w hile T ICs of the malignant tumors were mainly fast rise and fast drop and DVPCs were mainly biphasic . ② T he differences of quantitative parameters IM AX ,K 1 ,K2 ,mT T and RT of T ICs were statistically significant between the two groups ( P ＜0 .05) ,w hile those of A T and T T P were not ( P ＞ 0 .05 ) . ③ IM AX＝ 456 .2% ,K1 ＝109 .6 ,K2 ＝35 .2 ,RT＝7 .9 s ,mT T＝28 .1 s were the best cut‐off values for differential diagnosis . Among these parameters ,mT T with 28 .1 s had the highest diagnostic value ( sensitivity :81% ,specificity :77% ) . Conclusions The quantitative CEUS parameters can provide effective reference for differential diagnosis of orbit tumors in extraconal compartment .
