Primary clinical application of shear wave elastography combined with shear wave dispersion in differentiating diagnosis of focal liver lesions
10.3760/cma.j.issn.1004‐4477.2019.09.006
- VernacularTitle:超声剪切波黏弹性技术在肝肿瘤良恶性鉴别中的初步临床应用
- Author:
Qi ZHANG
1
;
Yi DONG
;
Daohui YANG
;
Lingyun YU
;
Yijie QIU
;
Wenping WANG
Author Information
1. 复旦大学附属中山医院超声科
- Keywords:
Shear wave elastography;
Shear wave dispersion;
Viscoelasticy;
Liver neoplasms;
Differential diagnosis
- From:
Chinese Journal of Ultrasonography
2019;28(9):766-770
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the initial clinical value of shear wave elastography ( SWE ) combined with shear wave dispersion ( SWD) in preoperatively differentiating diagnosis of focal liver lesions ( FLLs) . Methods Eighty‐three patients diagnosed as FLLs were prospectively enrolled from January to April 2018 in Zhongshan Hospital of Fudan University . M easurements of SWD and SWE both inner FLLs and surrounding liver parenchyma 2 cm away from the board lines of lesions were performed . ROIs were placed within the lesions and surrounding parenchyma 2 cm away from the lesions . In each ROI , measurements were performed 13 times . Histopathological results after operation were regarded as gold standard ,and the values of viscoelasticity in differentiating diagnosis of FLLs were analyzed . Results The final histopathological results showed that of all 83 cases ,20 cases were diagnosed as benign lesions ( 5 cases of focal nodular hyperplasia ,15 cases of hemangioma) ,and 63 cases as malignant lesions ( 12 cases of liver metastases ,51 cases of hepatocellular carcinoma) . T he SWE of benign lesions and malignant lesions were ( 9 .94 ± 8 .22) kPa ,and ( 13 .68 ± 7 .80) kPa( P ＜0 .05 ) . T he SWD of benign lesions and malignant lesions were ( 13 .47 ± 2 .76 ) ( m/s)/kHz ,and ( 15 .00 ± 3 .82 ) ( m/s)/kHz ( P ＜0 .05 ) . T he SWE ratio and SWD ratio of benign lesions to surrounding liver parenchyma were higher than those of malignant lesions( all P ＜
