Study on microscopic marginal extensions of malignant liver tumors based on tumor types and ultrasonic characteristics
10.3760/cma.j.issn.1004‐4477.2019.09.005
- VernacularTitle:基于超声特点及肿瘤类型的肝恶性肿瘤边缘浸润距离的研究
- Author:
Xian ZHONG
1
;
Xiaohua XIE
;
Jihui KANG
;
Bowen ZHUANG
;
Xiaoyan XIE
Author Information
1. 中山大学超声诊断与介入超声研究所 中山大学附属第一医院超声科
- Keywords:
Ultrasonography;
Contrast‐enhanced ultrasonography;
Liver tumors;
T umor micro‐invasion
- From:
Chinese Journal of Ultrasonography
2019;28(9):759-765
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationships between microscopic marginal extensions and tumor types ,and ultrasonic characteristics of malignant liver tumors . Methods Two‐dimensional ultrasonography , contrast‐enhanced ultrasonography and ultrasound‐guided biopsy of hepatic tumors and surrounding hepatic tissues were performed in 78 patients with malignant liver tumor . Pathological microscopic extensions were observed after hematoxylin‐eosin staining of biopsy specimens . Results T he microscopic marginal extension rates of hepatocellular carcinoma ( HCC) ,intrahepatic cholangiocarcinoma ( ICC) and metastatic liver cancer ( M LC) were 62 .5% ( 30/48 ) ,87 .5% ( 7/8 ) ,and 91 .0% ( 20/22 ) ,respectively . For tumors with well‐defined and poorly‐defined two‐dimensional ultrasound boundary ,microscopic marginal extension rates were 50% ( 14/28) ,and 86% ( 43/50) . T umor type and two‐dimensional ultrasound boundary were independent predictors for microscopic extension rate ( P ＜ 0 .05 ) . T he median microscopic extension distances of HCC ,ICC and M LC were 1 .0 ( 0 ,3 .0 ) mm ,4 .0 ( 2 .3 ,4 .0 ) mm ,and 2 .0 ( 1 .8 ,4 .0 ) mm ,respectively . T he distance of microscopic extension increased with tumor size . T umor type and tumor size were independent predictors for the distance of microscopic extension ( P ＜0 .05) . Conclusions ICC ,MLC ,and tumors with larger diameter or poorly‐defined two‐dimensional ultrasound boundary have a larger distance of microscopic extension .
