Effect of body mass index on the number of lymph nodes harvested in patients who underwent colorectal cancer resection
10.3969/j.issn.1000-8179.2019.16.458
- VernacularTitle:体质量指数对结直肠癌切除术中淋巴结检测数目的影响
- Author:
Dajia LIN
1
,
2
;
Jiansheng WU
;
Fangqin XUE
;
Linhao CHEN
;
Changqing ZENG
Author Information
1. 福建医科大学省立临床医学院(福州市350001)
2. 福建省立医院胃肠外科
- Keywords:
eywords: body mass index (BMI);
colorectal cancer resection;
number of lymph nodes harvest
- From:
Chinese Journal of Clinical Oncology
2019;46(16):822-826
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the effect of body mass index (BMI) on the number of lymph nodes (LNs) harvested in patients who underwent colorectal cancer resection. Methods: A retrospective analysis of 328 patients with colorectal cancer who were treated at Fujian Provincial Hospital between December 2014 and January 2017 was conducted. All patients underwent colorectal cancer resec-tion and were assigned into 2 groups:<12-LN group and≥12-LN group. Potential clinicopathological variables that might influence the number of LNs harvested were statistically analyzed. Results: Univariate analyses demonstrated that BMI (χ2=7.697, P=0.006), tumor location (χ2=7.900, P=0.048), and TNM stage (χ2=34.795, P<0.01) affected the number of LNs harvested. Logistic regression analysis re-vealed that BMI of≥25 kg/m2 and rectosigmoid location were associated with 2.557-and 1.731-fold increases in the number of LNs harvested, compared with BMI<25 kg/m2 group and other tumor locations, respectively. Conclusions: Higher BMI may decrease the number of LNs harvested in patients who underwent colorectal cancer resection and could affect the postoperative pathological stage. K
