Effeet of Timolol on Aqueous Humor Protein Concentration.
- Author:
Chung Sook AHN
1
Author Information
1. Department of Opthalmology, College of Medicine, Ewha Womans University, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Aqueous Humor*;
Cataract Extraction;
Humans;
Intraocular Pressure;
Molecular Weight;
Timolol*
- From:Journal of the Korean Ophthalmological Society
1986;27(6):1073-1076
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The Beta-adrenergic blocker(timolol maleate) decreases intraocular pressure by reducing the production of aqueous humor. Twenty patients scheduled to undergo cataract extraction were induced in study. After timolol maleate administration, we found the increase in the total protein concentration. By double-masked controlled study, 0.5% timolol maleate solution and normal saline were applied topically, and aqueous humor was aspirated during surgery. Total protein concentrations were determined by HPGFC. The total protein concentration as well as the concentration of high, medium and low molecular weight protein were elevated in the timololadministrated group. The relation of the levels of the three different molecular weight classes did not differ significantly between the timolol maleate group and the normal group.
