Risk factors for the development of Clostridium difficile colitis in a surgical ward.
10.4174/jkss.2012.83.1.14
- Author:
Min Jeong KIM
1
;
Byung Seup KIM
;
Jae Woo KWON
;
So Eun AHN
;
Seung Soon LEE
;
Hyoung Chul PARK
;
Bong Hwa LEE
Author Information
1. Department of Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea. bshlee@hallym.ac.kr
- Publication Type:Original Article
- Keywords:
Clostridium difficile;
Colitis;
Risk factors;
Colectomy
- MeSH:
Aged;
Centers for Disease Control and Prevention (U.S.);
Clostridium;
Clostridium difficile;
Colectomy;
Colitis;
Cross Infection;
Diarrhea;
Hospitalization;
Humans;
Length of Stay;
Multivariate Analysis;
Odds Ratio;
Polymerase Chain Reaction;
Retrospective Studies;
Risk Factors
- From:Journal of the Korean Surgical Society
2012;83(1):14-20
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Clostridium difficile colitis (CDC) is a nosocomial infection. We attempted to discover the risk factors for the development of CDC in patients admitted to our surgical ward. METHODS: We conducted a retrospective chart review of all patients admitted to our surgical ward between January 2010 and July 2011. CDC was confirmed when toxin A/B or toxin B polymerase chain reaction was detected in the stool and clinical symptoms, such as diarrhea, were present. We divided patients into the CDC and non-CDC groups, and compared the clinical features between the two groups. RESULTS: The rate of CDC occurrence was 0.4% (19/4,720 patients). Univariate analysis showed that colectomy (P < 0.001), hospital stays longer than 10 days (P < 0.001), aged over 55 years (P < 0.001) and transfer from medical ward (P = 0.009) were significant parameters for CDC. Multivariate analysis showed that colectomy (P < 0.001; odds ratio [OR], 8.405; 95% confidence interval [CI], 2.927 to 24.132) and hospital stays longer than 10 days (P = 0.035; OR, 10.253; 95% CI, 1.176 to 89.392) were high risk factors for CDC occurrence in the surgical ward. CONCLUSION: The risk factors for CDC in a surgical ward could be colectomy and a long duration of hospitalization. Therefore, clinicians should consider the possibility of CDC when patients undergo colectomy, are admitted for a long time, and have postoperative diarrhea.
