Effects of renal Na-Cl co-transporter on calcium homeostasis and bone metabolism
10.3760/cma.j.issn.1674-635X.2019.04.009
- VernacularTitle:肾脏钠氯协同转运蛋白调节钙平衡在骨代谢中的作用
- Author:
Bingbin ZHAO
1
;
Lei ZHANG
;
Limeng CHEN
Author Information
1. 100730 北京, 中国医学科学院, 北京协和医学院,北京协和医院肾内科
- Keywords:
Na-Cl co-transporter;
Calcium homeostasis;
Bone metabolism
- From:
Chinese Journal of Clinical Nutrition
2019;27(4):251-256
- CountryChina
- Language:Chinese
-
Abstract:
Osteoporosis is a global public health problem. The kidney, especially the Na-Cl co-trans-porter ( NCC) located in the renal distal tubular cells, which is an important transporter for urinary calcium reg-ulation, plays an important role in calcium homeostasis and bone metabolism. This review summarized recent re-searches on effects and mechanisms of NCC on calcium and bone metabolism.
