Preventive Effect of Tamsulosin on Postoperative Urinary Retention.
10.4111/kju.2012.53.6.419
- Author:
Mohammadreza MOHAMMADI-FALLAH
1
;
Sepehr HAMEDANCHI
;
Ali TAYYEBI-AZAR
Author Information
1. Urology, Nephrology & Kidney Transplant Research Center, Department of Urology, Imam Medical Center, Urmia University of Medical Sciences, Urmia, Iran. sepehrhamedanchi@yahoo.com
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
Adrenergic alpha-Antagonists;
Herniorrhaphy;
Tamsulosin;
Urinary retention
- MeSH:
Adrenergic alpha-Antagonists;
Anesthesia;
Catheterization;
Catheters;
Hernia;
Herniorrhaphy;
Humans;
Incidence;
Male;
Sulfonamides;
Urinary Retention
- From:Korean Journal of Urology
2012;53(6):419-423
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To investigate the prophylactic effect of Tamsulosin, a super-selective alpha-1a adrenergic blocking agent, on the development of urinary retention in men undergoing elective inguinal herniorrhaphy. MATERIALS AND METHODS: From May 2010 through November 2011, a total of 80 males who underwent elective inguinal herniorrhaphy in a university hospital were included in this study. Patients were randomly assigned to one of two groups. In group one (control), the patients were given two doses of placebo orally, 6 hours before surgery and 6 to 12 hours after surgery. Patients in group two were given 0.4 mg of Tamsulosin orally in the same manner as the placebo. All patients were closely followed for 24 hours post-operatively, and any voiding difficulties or urinary retention was recorded. RESULTS: There were 40 patients in group one (control group) and 40 patients in group two (Tamsulosin group). The patients' mean age was 64 years. In group one, 6 patients and in group two, 1 patient required catheterization. Thus, 15% of patients in group I and 2.5% of patients in group II had urinary retention. The difference in the requirement for catheterization was statistically significant (p=0.04). The technique of herniorrhaphy, the side of the body in which the hernia was located, the type of anesthesia, the duration of the surgery, and the severity of pre-operative urinary symptoms had no significant effect on the incidence of urinary retention. CONCLUSIONS: The use of perioperative Tamsulosin represents an effective strategy to reduce the risk of post-operative urinary retention following inguinal herniorrhaphy.
