Synchronous Urothelial Carcinoma of the Bladder and Urachal Adenoma with Subsequent Malignant Transformation.
10.4111/kju.2012.53.6.438
- Author:
David PAN
1
;
Yeng Kwang TAY
;
Scott DONNELLAN
Author Information
1. Department of Urology, Monash Medical Centre, Southern Health, Victoria, Australia. dpan1111@yahoo.com.au
- Publication Type:Case Report
- Keywords:
Synchronous;
Transformation;
Urachal adenocarcinoma;
Urachal adenoma;
Urothelial carcinoma
- MeSH:
Adenocarcinoma;
Adenoma;
Humans;
Metaplasia;
Urinary Bladder;
Urinary Bladder Neoplasms
- From:Korean Journal of Urology
2012;53(6):438-440
- CountryRepublic of Korea
- Language:English
-
Abstract:
Malignant transformation of urachal adenoma is exceedingly rare, with intestinal metaplasia as the most common contributing mechanism. It is recommended that a urachal adenoma be regarded as a pre-malignant condition and be subject to endoscopic surveillance. A local en block excision of the tumor mass with urachalectomy and umbilectomy results in possible long-term survival. The median survival after platinum-based chemotherapy is limited for patients with extravesical disease. Here we report a case of synchronous urothelial carcinoma of the bladder and urachal adenoma that transformed into adenocarcinoma.