Study on hydrophilic chemical constituents from Thesium Chinensis Turcz
10.3969/j.issn.1006-0111.2018.03.017
- VernacularTitle:百蕊草亲水性化学成分研究
- Author:
Weidong XUAN
1
;
Zhengping FAN
;
Shuigen HU
;
Dedong XU
Author Information
1. 解放军411医院药学科
- Keywords:
Thesium chinensis Turcz;
chemical constituents;
flavonoid glycosides
- From:
Journal of Pharmaceutical Practice
2018;36(3):270-273
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the hydrophilic chemical constituents from Thesium Chinensis Turcz.Methods The water extract of Thesium Chinensis Turcz.was adsorbed onto AB-8 resin column and eluted with 50% ethanol to give the hydrophilic portion TT50.TT50 was further separated and purified by repeated column chromatography on silica gel,Sephadex LH-20.The structures of these purified compounds were identified by NMR spectral analysis and comparison with the reported data.Results Six compounds were isolated and identified as kaempferol(1),kaempferol-3-O-glucoside(2),kaepmferol-3,7-di-O-β-D-glucopyranoside(3),kaempferol-3-O-L-rhamnopyranosyl(1 → 2)-β-D-glucopyranoside(4),kaemperol-3-O-α-L-rham-nopyranosyl(1→2)-[6-O-acetyl]-β-D-glucopyranoside(5),rutinoside(6).Conclusion The main constituents of TT50 were kaempferol glycosides.Compounds 4 and 5 were isolated from this plant for the first time.
