Progress of tanshinone ⅡA on the mechanism of inflammatory response after cer-ebral ischemia
10.3969/j.issn.1006-0111.2018.02.003
- VernacularTitle:丹参酮ⅡA对脑缺血后炎性反应影响机制的研究进展
- Author:
Jingjing FENG
1
;
Tiejun LI
;
Yuefan ZHANG
Author Information
1. 安徽中医药大学药学院
- Keywords:
tanshinone ⅡA;
cerebral ischemia;
inflammatory response
- From:
Journal of Pharmaceutical Practice
2018;36(2):108-111
- CountryChina
- Language:Chinese
-
Abstract:
Tanshinone ⅡA is a kind of phenanthraquinone derivatives derived from Salvia miltiorrhiza,which is one of the main active components of Danshen to play the protective role of cerebral ischemic injury.Inflammation plays an important role in the pathogenesis of cerebral ischemia.In recent years,much evidence shows that immune cells,adhesion molecules,in-flammatory mediators have been involved in the pathogenesis of immune response in the central nervous system through induc-tion or regulation of cerebral ischemia.In this paper,the research progress of mechanism of inflammatory response of tanshi-none ⅡA after cerebral ischemia was reviewed,which provided a new idea for the study of the protective mechanism of tanshi-none ⅡA in cerebral ischemia.
