The individualized anti-infective treatment strategy for a critically ill patient
10.3969/j.issn.1006-0111.2017.06.018
- VernacularTitle:1例重症患者抗感染个体化给药策略分析
- Author:
Xiaoping SHI
1
;
Qianzhou LYU
;
Wanhua YANG
;
Jie FANG
Author Information
1. 复旦大学附属中山医院药剂科
- Keywords:
acute generalized exanthematous pustulosis;
therapeutic drug monitoring;
vancomycin;
amikacin
- From:
Journal of Pharmaceutical Practice
2017;35(6):554-558
- CountryChina
- Language:Chinese
-
Abstract:
Objective To design individualized anti-infective therapy for a critically ill patient .Methods Based on patho-physiological conditions and therapeutic drug levels ,clinical pharmacists assisted physicians to optimize individual anti-infective medication regimens for a patient with acute generalized exanthematous pustulosis secondary to blood stream infection and pul-monary infection .Results The patient responded poorly to initial treatment .After the medication regimen adjustments byclini-cal pharmacists according to the individual situation and therapeutic drug monitoring results ,patient′s condition was improved and the infection was under control .Conclusion The key to successful treatment is to ensure the dosage administered to the critically ill patients reach the target value of pharmacokinetics and pharmacodynamics .
