Quality standards for Kangkeling mixture
10.3969/j.issn.1006-0111.2017.06.014
- VernacularTitle:康咳灵合剂质量标准研究
- Author:
Min PENG
1
;
Xiaodong TONG
;
Shuiying YANG
;
Yan XU
;
Xiaoyan JIANG
Author Information
1. 南通市中医院
- Keywords:
Kangkeling mixture;
TLC;
HPLC;
quality standard
- From:
Journal of Pharmaceutical Practice
2017;35(6):539-542
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish quality standards for Kangkeling mixture .Methods Ardisiae Japonicae Herba ,Ste-monae Radix were identified by TLC .The content of bergenin was determined by HPLC .Lichrospher C18 column(5 μm , 4 .6 mm × 250 mm)was used with methanol-water (20:80) as mobile phase .The flow rate was 1 .0 ml/min .Column temper-ature was 30 ℃ and the detection wavelength at 275 nm .Results The linear range of bergenin was in the range of 0 .0648-0 .648 μg (r=0 .9998) .The average recovery was 100 .24％ (RSD=1 .9％ ,n=6) .Conclusion The method is simple ,spe-cific and sensitive .It can be used to control the quality of Kangkeling mixture .
