Research progress on drugs in osteoporosis therapy
10.3969/j.issn.1006-0111.2017.06.003
- VernacularTitle:抗骨质疏松治疗药物研究的新进展
- Author:
Wenbin JIA
1
;
Chao LIU
;
Yan ZOU
Author Information
1. 海军青岛第一疗养院药剂科
- Keywords:
osteoporosis;
drugs;
therapy;
anti-resorptive drugs;
bone-anabolic drugs;
bone mineralization-acceleration drugs
- From:
Journal of Pharmaceutical Practice
2017;35(6):490-494,542
- CountryChina
- Language:Chinese
-
Abstract:
Osteoporosis (OP) is a systemic bone metabolism disease characterized by a systemic impairment of bone mass ,strength ,and microarchitecture ,which will be result in increasing the propensity of fragility fractures .In recent years , OP becomes a worldwide health problem and a hotspot in medical research due to its increasing incidence .Anti-resorptive drugs inhibit osteoclast differentiation and maturation in order to reduce bone resorption ;Bone-anabolic drugs promote the bone for-mation function of osteoblast and reconstruct bone tissue ;Bone mineralization-acceleration drugs are the basic material for pre-vention and treatment of osteoporosis ,including calcium and vitamin D ;Strontium ranelate is the representative drug of un-coupling agents .In this paper ,the current progress of osteoporosis treatments were reviewed including these proposed drugs .
