The extraction and acute toxicity testing of Moringa oleifera leaves and seeds
10.3969/j.issn.1006-0111.2017.04.011
- VernacularTitle:辣木叶和种子的提取及急性毒性评价
- Author:
Yan CHEN
1
;
Mei ZHANG
;
Jinping WANG
;
Feng YANG
Author Information
1. 陆军总医院药理科
- Keywords:
Moringa oleifera;
superfine powder process;
acute toxicity testing
- From:
Journal of Pharmaceutical Practice
2017;35(4):334-336,370
- CountryChina
- Language:Chinese
-
Abstract:
Objective To test the acute toxicity and determine the safe dose range of Moringa oleifera leaves and seeds.Methods Acute toxicity tests were performed based on the documented experimental designs in Research Methods of Pharmacology of Chinese Traditional Medicine.Results The maximum tolerated dose of the superfine powder and alcoholic-aqueous extract of Moringa oleifera leaves were 0.4 g/20 g and 0.8 g/20 g for mice.The safe dose for human is under or equal to 10 g/50 kg and 20 g/50 kg.Conclusion Moringa oleifera leaves were safe for medical and food use.The further research and development is warranted for this plant.
