Optimization of the water extraction process for Zhuyu Zhitong gel paste by or-thogonal experiment
10.3969/j.issn.1006-0111.2017.02.012
- VernacularTitle:正交试验优选逐瘀止痛凝胶膏剂的水提工艺研究
- Author:
Dong YANG
1
;
Jianyun BI
;
Yanwei GUO
;
Zhenyu ZHANG
Author Information
1. 潍坊市益都中心医院
- Keywords:
Zhuyu Zhitong;
gel paste;
paeoniflorin;
orthogonal experiment
- From:
Journal of Pharmaceutical Practice
2017;35(2):146-149
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the water extraction process of Zhuyu Zhitong gel paste .Methods With the yields of paeoniflorin and the dry paste as target ,the water extraction process of Zhuyu Zhitong gel paste was optimized by an orthogo-nal experimental design based on the single factor experiment .Results The optimized water extraction process of Zhuyu Zhi-tong gel paste was soaking the materials for 1 h with 8 times of water ,then extracting 1 .5 h for three times with the same a-mount of water .Conclusion The optimized extraction process was consistent ,reasonable and feasible for large production .