High purity preparation and identification of three phthalide compounds from Apium graveolens
10.3969/j.issn.1006-0111.2017.02.010
- VernacularTitle:高纯度单体制备及结构鉴定芹菜籽中3种苯酞成分
- Author:
Wenhui CHEN
1
;
Gang SHEN
;
Haisheng CHEN
Author Information
1. 第二军医大学药学院天然药物化学教研室
- Keywords:
A pium graveolens;
3-n-butylphthalide;
sedanenolide;
sedanolide;
structure identification
- From:
Journal of Pharmaceutical Practice
2017;35(2):138-140
- CountryChina
- Language:Chinese
-
Abstract:
Objective Isolation , purification and structure identification of phthalides from A pium graveolens L . Methods Silica gel column and preparative TLC chromatography were used to isolate and purify the phthalide compounds .The structures of those compounds were determined through spectral analysis .Results Three pure compounds were identified as 3-n-butylphthalide ,sedanenolide and sedanolide .Conclusion Three pure phthalide compounds can be used as analytical reference standard for quantitative analysis of A .graveolens .