Signaling pathways involved in radioprotection
10.3969/j.issn.1006-0111.2017.01.003
- VernacularTitle:辐射防护相关信号通路研究现状
- Author:
Jing WANG
1
;
Yuefan ZHANG
;
Tiejun LI
Author Information
1. 安徽中医药大学药学院
- Keywords:
ionizing radiation;
radioprotection;
signaling pathway
- From:
Journal of Pharmaceutical Practice
2017;35(1):8-11
- CountryChina
- Language:Chinese
-
Abstract:
People do have some risks of exposing to the radiation during their daily life .Longtime or megadose ionizing radiation can induce tissue damage ,which is related to cell apoptosis ,necrosis and inflammation ,etc ..Currently ,more and more radio protective agents were developed and several signaling pathways were involved .NFκB ,MAPK ,PI3k/Akt ,p53 and STAT3 signaling pathways were reviewed in this article .