Analysis of liposoluble chemicals from Achillea Alpina L .by GC-MS
10.3969/j.issn.1006-0111.2016.06.011
- VernacularTitle:气相色谱唱质谱联用法测定蓍草中的脂溶性成分
- Author:
Ruishu LIANG
1
;
Liyan XIONG
;
Ling LI
;
Chuan ZHANG
Author Information
1. 第二军医大学药学院
- Keywords:
Achillea alpina L .;
liposoluble chemicals;
GC-MS
- From:
Journal of Pharmaceutical Practice
2016;34(6):526-529
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the chemical structures for the components in the liposoluble portion of Achillea alpi-na L .by gas chromatography/mass spectrometry (GC-MS) .Methods Achillea alpina L .was extracted with 95% alcohol and petroleum ether .The chemical compositions in the extract were analyzed with GC-MS .The structures were identified by comparing to the authentic samples and searching NIST 10 database .The relative content of each compound in the extract was calculated by area normalization method .Results Twenty-nine compounds were separated and identified ,which accounted for 82 .74% of petroleum ether extract .The major constituents were octamethylpicen-3-ol (33.16% ) ,Lup20(29)-en-3-ol ,acetate (3b) (10 .99% ) , n-Hexadecanoic acid (7 .98% ) , Stigmasterol (3 .68% ) , Octadecanoic acid (3 .55% ) , Friedelan-3-one (3 .51% ) .Conclusion This simple and accurate method can be used for the assay of liposoluble chemicals from Achillea alpi-na L .The results provide a foundation for pharmacological research and better use the resource of Achillea alpina L .
