The relationship between DC-CIK and colorectal cancer prognoses and its influen-cing factors
10.3969/j.issn.1006-0111.2016.04.022
- VernacularTitle:DC-CIK与结直肠癌患者预后的关系和影响因素
- Author:
Yue CAO
1
;
Xijing YANG
;
Fuping ZHOU
;
Qian ZHANG
;
Qijun QIAN
Author Information
1. 福建医科大学第一临床医学院
- Keywords:
colorectal cancer;
prognosis;
dendritic cell-cytokine-induced killers (DC-CIK);
drug targeting therapy
- From:
Journal of Pharmaceutical Practice
2016;34(4):366-371
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss dendritic cell-cytokine-induced killer (DC-CIK ) cell therapy effects and clinical out-comes in patients with colorectal cancer in order to have better clinical treatment .Methods A retrospective analysis of the data of 66 patients with colorectal cancer from the Biological Therapy Department of the Eastern Hepatobiliary Surgery Hospital was performed from January 2012 to January 2014 ,and then was followed up .Taking gender ,age ,degree of pathological differen-tiation ,TNM staging ,surgical methods ,and targeted therapy as the research basis ,by the Kaplan-Meier single factor and Cox multiple factors analysis we mainly discuss the DC-CIK cell treatment′s effect on the prognoses of patients .Results Kaplan-Meier single factor analysis results indicate :to a certain extent ,DC-CIK cell therapy can improve the prognoses of patients ;Cox multi-factor analysis results indicate whether accepting DC-CIK cell therapy is an independent factor influencing the prog-noses of patients .Conclusion DC-CIK cells therapy can improve the prognoses of patients with colorectal cancer .
