Identification and determination of scutellarin in compound granule tetrandra
10.3969/j.issn.1006-0111.2016.03.013
- VernacularTitle:复方汉防己颗粒中野黄芩苷的定性鉴别和含量测定
- Author:
Shuyu ZHANG
1
;
Jianjiang XU
;
Yanli YU
;
Yunsheng BI
;
Wenjing ZHAO
;
Qian LIU
;
Tongqi LIU
Author Information
1. 济南军区总医院药剂科
- Keywords:
compound granule tetrandra;
sculellaria barbata;
scutellarin;
TLC;
HPLC
- From:
Journal of Pharmaceutical Practice
2016;34(3):245-248
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop the methods for identification and determination of scutellarin in compound Granule Tetrandra .Methods A TLC method was used to identify quality for scutellarin ,and a HPLC method was used to determine the content of scutellarin .Results The spot was clear in TLC identification without interference of negative control .The sam-ple size of scutellarin had a good linear relationship with peak area r=0 .9996(n=5)when ranged from 22 .4~156 .8 μg/ml , with the average recovery rate 97 .79% ( RSD=0 .32% ,n=6) .Conclusion The method is simple ,with good specificity and reproducibility ,which can be used as the quality control for this preparation .
