The high adaptability and metabolism of Candida albicans
10.3969/j.issn.1006-0111.2016.02.006
- VernacularTitle:白念珠菌的高适应性与代谢
- Author:
Shuang BI
1
;
Dandan HU
;
Yuanying JIANG
;
Yan WANG
Author Information
1. 第二军医大学药学院新药研究中心
- Keywords:
Candida albicans;
high adaptability;
metabolism
- From:
Journal of Pharmaceutical Practice
2016;34(2):116-118,173
- CountryChina
- Language:Chinese
-
Abstract:
Pathogenic Candida albicans has a high degree of adaptability to environment,which is evidenced by its a-daptability to various conditions,including its symbiosis with the host,growth in host tissues during invasion,and survival un-der antifungal treatment.The growth and reproduction of C.albicans is accompanied with metabolism process.C.albicans can use a wide range of carbon and nitrogen sources,and it is sensitive to the alteration of nutrition.Recent studies reveal that the environment affects the metabolism of C.albicans,whilst C.albicans regulates its metabolism to adapt to the environment. Therefore,further study on the relationship between metabolism and high adaptability of C.albicans is helpful to discover no-vel antifungal targets.