Research progress in the effect of CYP 2C19 gene polymorphisms on drug metabo-lism
10.3969/j.issn.1006-0111.2015.06.008
- VernacularTitle:CYP2C19基因多态性对药物代谢影响的研究进展
- Author:
Jing PENG
1
;
Wei LIU
Author Information
1. 解放军88医院
- Keywords:
CYP2C19;
polymorphism;
proton pump inhibitor;
voriconazole;
clopidogrel
- From:
Journal of Pharmaceutical Practice
2015;(6):508-512
- CountryChina
- Language:Chinese
-
Abstract:
Drug metabolism and drug-drug interactions were associated with the single nucleotide polymorphisms of CYP .The relationship between CYP2C19 polymorphisms and metabolism as well as interactions of proton pump inhibitors , voriconazole and clopidogrel were reviewed to provide evidence for personalized medication .
